HW functional medicine · 14 min read · 2,723 words

The Comprehensive Elimination Diet: Your Step-by-Step Guide

No blood test can tell you with certainty which foods are driving your symptoms. IgG food sensitivity panels offer clues, but they carry significant false-positive and false-negative rates.

By William Le, PA-C

The Comprehensive Elimination Diet: Your Step-by-Step Guide

Why the Elimination Diet Is the Gold Standard

No blood test can tell you with certainty which foods are driving your symptoms. IgG food sensitivity panels offer clues, but they carry significant false-positive and false-negative rates. Your body is the ultimate laboratory, and the elimination diet is the most reliable experiment you can run in it.

The Institute for Functional Medicine considers the elimination diet foundational — often the first therapeutic intervention, before any supplement or medication. The logic is simple: if a food you eat three times a day is silently fueling inflammation, gut damage, and immune activation, no amount of supplements can overcome that daily assault. You have to find the fire before you can put it out.

This is not a weight-loss diet. It is a controlled diagnostic experiment with one subject: you. And when done properly, it delivers data no lab test can match.

Preparation Phase: One Week Before You Start

Preparation is the difference between success and a frustrated collapse on day four. Invest one full week before your start date.

Pantry clean-out. Remove trigger foods from your kitchen. If they are in the house, you will eat them — willpower is a depleting resource. Box up the gluten, dairy, sugar, corn, soy, and processed foods. Give them away or store them out of sight. This is temporary.

Meal planning. Map out your first week of meals. Write it down. Batch-cook on Sunday — a large pot of bone broth, roasted sweet potatoes, grilled chicken breasts, a pot of rice. Having food ready is your insurance against convenience-food relapse.

Go shopping. Stock your kitchen with approved foods (full list below). Buy more than you think you need. Running out of options is the number one reason people break the elimination early.

Wean caffeine gradually. If you drink coffee daily, do not quit cold turkey on Day 1. Taper over 5 to 7 days. Day 1-2: half your usual amount. Day 3-4: quarter your usual amount. Day 5-7: switch to green tea only. Going from three cups of coffee to zero overnight produces withdrawal headaches, fatigue, and irritability that will make the elimination miserable and confuse your symptom tracking.

Set your start date. Choose a period without travel, holidays, or major social events. Tell your family, partner, or housemates what you are doing and why. Their understanding and cooperation — or at least their non-sabotage — matters.

Start your food and symptom journal. Begin tracking now, before the elimination, so you have a baseline. Record everything you eat and every symptom you notice — energy, digestion, mood, sleep, skin, joints, headaches, brain fog. This pre-elimination baseline is the data you will compare against.

Phase 1: Elimination (21-28 Days)

Twenty-one days is the minimum for antibodies from reactive foods to clear your system. Twenty-eight days is better for people with autoimmune conditions or long-standing inflammation. Do not cut corners here. A 14-day elimination produces unreliable data.

Foods to REMOVE

  • Gluten — All wheat, barley, rye, spelt, kamut, triticale, and anything made from them (bread, pasta, crackers, most baked goods, soy sauce, many condiments)
  • Dairy — All of it. Milk, cheese, yogurt, butter, cream, whey protein, casein, caseinates, ice cream. No exceptions. Ghee is borderline — remove it for the strictest protocol, or include it if you are not doing an autoimmune variant
  • Eggs — Whites and yolks, in all forms
  • Corn — Including corn syrup, cornstarch, dextrose, maltodextrin, corn oil, popcorn, tortilla chips
  • Soy — Soy sauce, tofu, tempeh, edamame, soy protein isolate, soy lecithin (pervasive in processed food)
  • Peanuts — Peanut butter, peanut oil (peanuts are legumes, not tree nuts, and are highly allergenic)
  • Sugar and artificial sweeteners — Refined sugar, high-fructose corn syrup, aspartame, sucralose, saccharin, acesulfame-K. Small amounts of raw honey or maple syrup are acceptable if needed for palatability
  • Alcohol — All forms, no exceptions
  • Caffeine — Eliminate or limit to one cup of green tea daily
  • Processed and packaged foods — If it has a long ingredient list, put it back
  • Nightshades (optional, recommended for autoimmune) — Tomatoes, white potatoes, bell peppers, hot peppers, eggplant, goji berries, paprika, cayenne
  • Shellfish (optional) — Shrimp, crab, lobster, mussels, clams

Foods to ENJOY

  • All vegetables (except nightshades if removed) — leafy greens, cruciferous (broccoli, cauliflower, cabbage, Brussels sprouts, kale), root vegetables (sweet potato, beets, carrots, parsnips, turnips), squash, zucchini, cucumber, celery, asparagus, artichoke, mushrooms, onions, garlic, leeks
  • All fruits — emphasize berries (blueberries, raspberries, blackberries, strawberries) for their polyphenol content; moderate higher-sugar tropical fruits
  • Rice — white or brown, both are fine
  • Quinoa — a complete protein pseudograin
  • Sweet potato — a versatile staple
  • Oats — certified gluten-free only (conventional oats are heavily cross-contaminated with wheat)
  • All meats — grass-fed beef, pasture-raised poultry, wild game, lamb, pork. Quality matters: grass-fed and pasture-raised when budget allows
  • Fish — wild-caught salmon, sardines, mackerel, cod, halibut, trout. Avoid high-mercury species (swordfish, king mackerel, tilefish, ahi tuna) in excess
  • Beans and lentils — unless you are following an autoimmune protocol (AIP), which removes legumes
  • Nuts and seeds — almonds, walnuts, cashews, pecans, macadamia, pumpkin seeds, sunflower seeds, hemp seeds, flaxseed, chia seeds, tahini (except peanuts, which are removed)
  • Healthy fats — extra virgin olive oil, coconut oil, avocado oil, flaxseed oil
  • Avocado — eat freely, excellent source of potassium and monounsaturated fat
  • Herbs and spices — all fresh and dried herbs, ginger, turmeric, cinnamon, cumin, coriander, basil, oregano, rosemary, thyme, sea salt, black pepper
  • Bone broth — homemade or store-bought with clean ingredients (chicken or beef bones simmered 12-24 hours with apple cider vinegar, vegetables, herbs)
  • Herbal teas — chamomile, peppermint, ginger, rooibos, tulsi, lemon balm
  • Coconut products — coconut milk (full-fat canned, no guar gum), coconut cream, shredded coconut, coconut aminos (soy sauce replacement)

Sample 7-Day Meal Plan

Day 1

  • Breakfast: Sweet potato hash with ground turkey, sauteed kale, diced onions, and sliced avocado
  • Lunch: Large mixed greens salad with grilled chicken, cucumber, shredded carrots, beets, pumpkin seeds, olive oil and lemon dressing
  • Dinner: Baked wild salmon with roasted broccoli and cauliflower, side of white rice
  • Snack: Apple slices with almond butter

Day 2

  • Breakfast: Smoothie — full-fat coconut milk, frozen blueberries, handful of spinach, ground flaxseed, collagen peptides
  • Lunch: Bone broth soup with shredded chicken, zucchini noodles, carrots, celery, fresh dill
  • Dinner: Grass-fed beef burger (no bun) wrapped in butter lettuce with avocado, caramelized onions, and sweet potato fries baked in avocado oil
  • Snack: Celery sticks with tahini, handful of walnuts

Day 3

  • Breakfast: Coconut yogurt (unsweetened) topped with mixed berries, toasted coconut flakes, and hemp seeds
  • Lunch: Turkey and avocado collard green wraps with shredded cabbage, carrots, and cucumber, dipped in coconut aminos
  • Dinner: Lamb chops with roasted root vegetables (parsnips, beets, carrots) and sauteed Swiss chard with garlic
  • Snack: Pear with a handful of macadamia nuts

Day 4

  • Breakfast: Warm rice porridge with coconut milk, cinnamon, sliced banana, and chia seeds
  • Lunch: Leftover lamb over mixed greens with olive oil, lemon, and fresh herbs
  • Dinner: Chicken stir-fry with broccoli, bok choy, mushrooms, snap peas, and ginger in coconut aminos, served over white rice
  • Snack: Guacamole with carrot and cucumber sticks

Day 5

  • Breakfast: Homemade turkey breakfast sausage patties (ground turkey, sage, thyme, garlic, salt, pepper) with sauteed spinach and roasted sweet potato rounds
  • Lunch: Canned wild sardines over arugula with olive oil, lemon juice, sliced radishes, and capers
  • Dinner: Slow-cooker chicken thighs with artichoke hearts, olives, lemon, and rosemary over cauliflower rice
  • Snack: Banana with sunflower seed butter

Day 6

  • Breakfast: Berry smoothie bowl — frozen mixed berries, coconut milk, banana, topped with pumpkin seeds, coconut flakes, and sliced kiwi
  • Lunch: Leftover chicken with roasted butternut squash and a large green salad
  • Dinner: Wild-caught cod with roasted asparagus and beets, drizzled with lemon-herb olive oil, side of quinoa
  • Snack: Plantain chips (baked in coconut oil) with guacamole

Day 7

  • Breakfast: Ground beef and sweet potato breakfast skillet with mushrooms, onions, and fresh rosemary
  • Lunch: Nori wraps filled with canned salmon, avocado, cucumber, and shredded carrots, with coconut aminos for dipping
  • Dinner: Roasted whole chicken with root vegetables (carrots, parsnips, turnips, onion), side salad with olive oil vinaigrette
  • Snack: Homemade trail mix — walnuts, pumpkin seeds, sunflower seeds, coconut flakes, unsweetened dried cranberries

Survival Tips

  • Cook at home. Restaurant food contains hidden ingredients — butter, soybean oil, wheat-based sauces, dairy in unexpected places. Home cooking gives you total control.
  • Read every label. Soy sauce contains wheat. Deli meat often contains dairy (casein, whey) and corn-derived dextrose. “Natural flavors” can hide anything. Read the ingredients, not just the front label.
  • “May contain” is okay. “May contain traces of wheat/dairy/soy” is a cross-contact warning for people with true IgE allergies (anaphylaxis risk). For an elimination diet testing sensitivities, this trace-level cross-contact is not relevant. Buy the product.
  • Batch cook protein on Sunday. Grill chicken, brown ground beef, roast a whole chicken. Having protein ready in the fridge eliminates the “I have nothing to eat” crisis.
  • Keep emergency snacks accessible. Approved bars (read the label — Larabars, RX Bars without dairy), individual nut butter packets, trail mix, fruit. Keep them in your bag, your car, your desk drawer.
  • Eat enough. This is the most common mistake. If you are hungry and exhausted, you are not eating enough fat and protein. Add avocado, olive oil, coconut, nuts, and seeds liberally. This is not a calorie-restriction diet.

What to Expect During Elimination

Days 1-7: Withdrawal. Headaches, fatigue, irritability, brain fog, intense cravings (especially sugar and gluten — these generate opioid-like peptides called gliadorphins and casomorphins that your brain has been dependent on). Possible changes in bowel habits. This is recalibration, not a sign the diet is wrong. Drink extra water, sleep more, and push through. It is temporary.

Days 7-14: Clearing. Symptoms begin lifting. Energy improves. Bloating decreases. Skin starts clearing. Sleep quality improves. Brain fog lifts. Your body is showing you what it feels like without chronic inflammatory triggers.

Days 14-28: Baseline. This is your clean baseline — the “you” without interference. Pay close attention. Many patients say they forgot what normal felt like. Symptoms they attributed to aging — afternoon fatigue, joint stiffness, skin issues, brain fog — were actually food reactions all along.

Phase 2: Reintroduction (6-8 Weeks)

This is where the real diagnostic power lives. The elimination reveals how good you can feel. The reintroduction identifies exactly which foods were causing problems. Skip this phase and you have wasted the entire effort.

Order of Reintroduction (Least Reactive First)

Reintroduce one food category at a time, in this order:

  1. Days 1-3: Eggs — Start with egg yolks only on Day 1 (cooked, 2-3 yolks). Yolks are far less reactive than whites. If yolks are tolerated, test whole eggs on Day 2 (2-3 whole eggs). Then remove eggs and observe for 2-3 days.
  2. Days 4-6: Dairy (graduated) — Day 4: butter or ghee (lowest protein). Day 5: plain yogurt or kefir (fermented, partially predigested). Day 6: aged cheese. Then remove all dairy and observe 2-3 days. If no reaction to these, test fresh milk and soft cheese separately later.
  3. Days 7-9: Gluten-free grains — Test corn (polenta, corn tortilla) on Day 7. Test oats (if not already included) on Day 8. Remove and observe.
  4. Days 10-12: Soy — Start with fermented soy (miso, tempeh) on Day 10. Test processed soy (tofu, soy milk) on Day 11. Remove and observe.
  5. Days 13-15: Nightshades — Test cooked tomato on Day 13, white potato on Day 14, bell pepper on Day 15. Remove and observe.
  6. Days 16-18: Gluten — This goes near the end because it is one of the most common and most impactful triggers. Eat bread, pasta, or crackers containing wheat — 2-3 servings on Day 16. Then remove completely for 3 full days and observe carefully. Gluten reactions can be delayed up to 72 hours.
  7. Days 19-21: Peanuts — Test peanut butter, 2-3 tablespoons on Day 19. Remove and observe.
  8. Continue with any other removed foods (shellfish, specific legumes, caffeine, alcohol) one at a time.

The Reintroduction Method

This protocol must be followed precisely, or the data is useless:

  1. Choose one food. Only one category at a time. Never test two foods simultaneously.
  2. Eat it 2-3 times on Day 1 in meaningful quantities — a full serving each time, not a tiny taste.
  3. Remove it completely for 2-3 days. Return to the full elimination diet.
  4. Record everything. Track every symptom — digestive, neurological, musculoskeletal, skin, respiratory, cardiovascular, general. Use your journal. Be specific about timing and severity.
  5. If no reaction after 72 hours — that food is cleared. Add it back to your diet and move to the next food.
  6. If a reaction occurs — remove that food, wait until all symptoms resolve completely (may take 2-5 days), then proceed to the next food.

Symptoms to Watch For

Reactions can appear within minutes or take up to 72 hours. This is why the observation period matters.

Gastrointestinal: Bloating, gas, abdominal pain or cramping, diarrhea, constipation, nausea, acid reflux

Neurological: Headache or migraine, brain fog, fatigue or energy crash, insomnia or disrupted sleep, mood changes (irritability, anxiety, low mood, agitation)

Musculoskeletal: Joint pain or stiffness (especially in hands, knees, and shoulders), muscle aches, general body soreness

Skin: Rash, hives, acne breakout, eczema flare, itching, flushing, rosacea flare

Respiratory: Nasal congestion, postnasal drip, sinus pressure, throat clearing, sneezing

Cardiovascular: Racing heart or palpitations, elevated pulse (track your resting heart rate — an increase of 10+ BPM after a food challenge is significant)

General: Water retention and sudden weight gain (1-3 lbs overnight from inflammation-driven fluid retention), dark circles under eyes (allergic shiners), facial puffiness, generalized swelling

After the Elimination: Building Your Personalized Diet

You now have data no lab test could provide. Organize your findings:

Green light foods — No reaction. Eat freely and regularly.

Yellow light foods — Mild or inconsistent reaction. You may tolerate these in small amounts, infrequently, on a rotation basis (not daily). Monitor for cumulative effects.

Red light foods — Clear reaction. Remove from your diet for now.

Red light foods are not necessarily permanent. A reaction means your body is currently reacting to that food — often because of underlying gut permeability, immune dysregulation, or microbiome imbalance. After 3 to 6 months of targeted gut healing (the IFM 5R protocol — Remove, Replace, Reinoculate, Repair, Rebalance), many previously reactive foods can be tolerated. The exceptions are celiac disease (lifelong gluten avoidance) and true IgE-mediated allergy (permanent).

Retest your red-light foods every 3 to 6 months. Your tolerance window expands as your gut heals. What triggered a migraine in month one may cause no reaction in month six — because the underlying gut dysfunction that was driving the reactivity has been addressed.

The Rotation Principle

To prevent developing new sensitivities, rotate your foods on a 4-day cycle. The same protein, grain, or major food does not repeat within a 4-day window. Monday’s salmon does not appear again until Friday. This gives your immune system time to clear immune complexes from each food before encountering it again. It also naturally promotes dietary diversity — which feeds a diverse, resilient microbiome.

The Bigger Picture

The elimination diet is not deprivation. It is the most honest conversation you can have with your own biology. Remove the noise, and the signal becomes unmistakable. Your body has been trying to tell you something through symptoms — bloating, fatigue, brain fog, joint pain, skin eruptions, mood crashes. The elimination diet is how you finally learn to hear what it has been saying.

This is where personalized medicine begins. Not in a genetics lab. Not in a doctor’s office. On your plate, in your kitchen, with your own careful observation. The data is yours, the insights are yours, and the power to act on them is yours.