Satchin Panda
Diabetes and Metabolic Syndrome: Pathways to Reversal
Type 2 diabetes (T2D) and metabolic syndrome represent the defining health crisis of modern civilization. Over 537 million adults worldwide live with diabetes, and metabolic syndrome — a cluster of insulin resistance, visceral obesity, hypertension, dyslipidemia, and hyperglycemia — affects an...
Therapeutic Fasting and Time-Restricted Eating: The Medicine of Not Eating
In a world obsessed with what to eat, the question of when to eat — and when not to eat — may be equally transformative. Therapeutic fasting and time-restricted eating (TRE) represent some of the most ancient and most scientifically validated health interventions, bridging the gap between...
Fasting Protocols: From Time-Restricted Eating to Extended Fasts
All fasting is not equal. A 12-hour overnight fast and a 5-day water fast activate fundamentally different metabolic pathways at different magnitudes.
Blue Light, Circadian Disruption, and the Consciousness Cost of Modern Lighting
For approximately 2.5 million years — the entire duration of the genus Homo — human biology was calibrated by one light source: the sun. Morning light was rich in blue wavelengths that activated the master circadian clock.
Circadian Sleep Optimization Protocol: Engineering the Consciousness Restoration Cycle
You are a circadian organism. Every cell in your body contains a molecular clock — a gene-protein feedback loop (involving the genes CLOCK, BMAL1, PER, and CRY) that cycles with a period of approximately 24.2 hours.
Circadian Rhythm Optimization: Light, Timing, and the Body's Inner Clock
Every cell in the human body contains a molecular clock — a set of interlocking transcription-translation feedback loops that oscillate with a period of approximately 24 hours. These clocks do not merely track time; they orchestrate virtually every physiological process, from gene expression and...